It must come in direct contact with the source of the odor in order to eradicate it. The odormute will not harm people, pets and plant life. Mix at a proportion of 1 tablespoon to 3,78 litre of warm water. Mix it with warm water until fully dissolved. For best results, dissolve Odormute in a 0.5 litre of warm water. Allow 5 - 10 minutes, mixing sometimes to make sure all powder is dissolved, then add this to the rest of the water. The enzymes are activated by adding warm water. Once activated enzymes must be used within four hours for best results. Water temperature should range between 45° F to 140° F, with the optimum temperature ranging from 70° F and 90° F. The freezing will not harm enzymes, however temperatures above 140° F will destroy them.